Compounds
Tirzepatide
Tirzepatide is a synthetic peptide agonist of the GIP and GLP-1 receptors and the active ingredient of Mounjaro, a prescription medicine approved by the US FDA (Mounjaro prescribing information, section 11).
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Retatrutide
Retatrutide (LY3437943) is an investigational triple agonist peptide at the glucagon, GIP and GLP-1 receptors (Coskun et al., Cell Metabolism, 2022), and the US FDA states it is not a component of any FDA-approved drug (FDA, unapproved GLP-1 drugs).
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Semaglutide
Semaglutide is a GLP-1 receptor agonist, an analogue of human GLP-1 with a fatty diacid side chain, and the active ingredient of Ozempic, a prescription medicine approved by the US FDA (Ozempic prescribing information, section 11).
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Cagrilintide
Cagrilintide is an investigational long-acting, lipidated analogue of the pancreatic hormone amylin (Kruse et al., Journal of Medicinal Chemistry, 2021), and the US FDA states it is not a component of any FDA-approved drug (FDA, unapproved GLP-1 drugs).
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Cagrilintide and semaglutide blend
CagriSema is the name used in published phase 3a trials for the investigational combination of cagrilintide, a lipidated amylin analogue, with the GLP-1 receptor agonist semaglutide (Garvey et al., New England Journal of Medicine, 2025).
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Liraglutide
Liraglutide is an analogue of human GLP-1 that acts as a GLP-1 receptor agonist, and it is the active ingredient of Victoza, a prescription medicine approved by the US FDA (Victoza prescribing information, section 11).
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BPC-157
BPC-157 is a synthetic pentadecapeptide derived from a gastric protein fragment that, according to a 2026 review, lacks the evidence needed for investigational or approved use under any major regulatory framework (Mateescu et al., Pharmaceutics, 2026).
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TB-500
TB-500 is a trade name: the product analysed in doping-control work contained N-acetylated LKKTETQ, a synthetic copy of residues 17 to 23 of the actin-binding protein thymosin beta-4 (Ho et al., Journal of Chromatography A, 2012), and the US FDA uses the name for that fragment (FDA, bulk substances with safety risks).
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GHK-Cu
GHK-Cu is the copper(II) complex of the tripeptide glycyl-L-histidyl-L-lysine (GHK), a peptide found in human plasma that binds copper with high affinity (Pickart et al., BioMed Research International, 2015).
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KPV
KPV (lysyl-prolyl-valine) is the C-terminal tripeptide of alpha-melanocyte-stimulating hormone (Brzoska et al., Endocrine Reviews, 2008), and the US FDA states it has identified no human exposure data on drug products containing it (FDA, bulk substances with safety risks).
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Ipamorelin
Ipamorelin is a synthetic pentapeptide growth hormone secretagogue, described by its developers as a GHRP-receptor agonist (Raun et al., European Journal of Endocrinology, 1998).
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CJC-1295
CJC-1295 was described by its developers as a tetrasubstituted analogue of human growth hormone-releasing factor (1-29) carrying a lysine with a maleimidopropionamide group at the C-terminus, designed to bond to serum albumin (Jetté et al., Endocrinology, 2005).
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Sermorelin
Sermorelin is the 1-29 amide fragment of human growth hormone-releasing factor, hGRF(1-29)NH2, listed under the name Geref in doping-control work (Knoop et al., Analytical and Bioanalytical Chemistry, 2016).
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Tesamorelin
Tesamorelin is a synthetic analogue of human growth hormone-releasing factor and the active ingredient of EGRIFTA SV, a prescription medicine approved by the US FDA (EGRIFTA SV prescribing information, section 11).
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MOTS-c
MOTS-c is a 16-amino-acid peptide encoded by a short open reading frame within the mitochondrial 12S rRNA gene (Lee et al., Cell Metabolism, 2015), and the US FDA states it has identified no human exposure data on drug products containing it (FDA, bulk substances with safety risks).
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Epitalon
Epitalon is a synthetic tetrapeptide, Ala-Glu-Asp-Gly, that was designed from the amino acid composition of a bovine pineal gland extract called Epithalamin (Araj et al., 2025).
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Selank
Selank is a synthetic heptapeptide, Thr-Lys-Pro-Arg-Pro-Gly-Pro, that the research literature describes as a peptide analogue of tuftsin (Konstantinopolsky et al., 2022).
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Semax
Semax is a synthetic heptapeptide that joins residues 4 to 7 of adrenocorticotropic hormone (Met-Glu-His-Phe) to a C-terminal Pro-Gly-Pro tripeptide (Magrì et al., 2016).
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AOD-9604
AOD-9604 is a synthetic 16-residue peptide made of the C-terminal fragment of human growth hormone from residues 177 to 191 with an extra tyrosine added at the N-terminus (Cox et al., 2015).
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PT-141 (bremelanotide)
Bremelanotide is a synthetic cyclic heptapeptide melanocortin receptor agonist, approved by the US FDA in 2019 as the prescription product Vyleesi (FDA prescribing information).
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Melanotan II
Melanotan II is a synthetic cyclic heptapeptide that PubChem describes as an analogue of alpha-melanotropin (alpha-MSH) (PubChem).
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Glutathione
Glutathione is a tripeptide in which glutamic acid is attached through its side chain to the N-terminus of cysteinylglycine, giving the sequence gamma-Glu-Cys-Gly (PubChem).
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Thymosin alpha-1
Thymalfasin is a chemically synthesised version of thymosin alpha-1, an acetylated 28-residue polypeptide identical to the human sequence, originally found in a thymus gland extract (PubChem).
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LL-37
LL-37 is the 37-residue peptide cleaved from the human cathelicidin antimicrobial peptide precursor, where it occupies residues 134 to 170 (UniProt P49913), and its international nonproprietary name is ropocamptide (PubChem).
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Kisspeptin
Kisspeptins are C-terminally amidated peptides cut from the human KiSS-1 precursor, which UniProt lists in four lengths: metastin (kisspeptin-54), kisspeptin-14, kisspeptin-13 and kisspeptin-10, all sharing the same final ten residues (UniProt Q15726).
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Oxytocin
Oxytocin is a nonapeptide hormone found in mammalian pituitary extracts; a synthetic version is approved by the US FDA as Pitocin, whose label describes the hormone as prepared synthetically (FDA prescribing information).
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IGF-1 LR3
IGF-1 LR3 is a recombinant analogue of insulin-like growth factor I in which Glu3 is replaced by arginine and a 13-residue N-terminal extension is attached, first described as Long [Arg3]-IGF-I (Francis et al., 1992; Milner et al., 1995).
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Follistatin
Follistatin is a large, cysteine-rich human glycoprotein that UniProt records as a 344-residue precursor with a 29-residue signal peptide, 18 disulfide bonds and two N-linked glycosylation sites (UniProt P19883).
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